The Comprehensive Center for Chest Diseases (CCCD) combines both medical and scientific expertise from
various specialized disciplines. Due to the close cooperation between all institutions and professions at the Medical University of Vienna and the Vienna General Hospital, a holistic approach in prevention, diagnosis,
management, therapy and prophylaxis of functional and oncological diseases of the thoracic organs is followed. These include the lungs, the thoracic wall, the diaphragm, the mediastinum, the esophagus, the thymus gland as well as the trachea.
The CCCD aims at continuously improving and further developing patient treatment, research, education and
training in the field of lung and thoracic diseases.
Current developments in thoracic surgery (video in German)
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Thoracic surgery covers a broad spectrum of diseases that are treated: Oncologic thoracic surgery, functional thoracic surgery, end-stage lung disease with transplantation and lung replacement therapy. In this video, Clemens Aigner from the Department of Thoracic Surgery at MedUni Vienna and Vienna General Hospital talks about lung-preserving surgery for early-stage lung cancer, translational research in thoracic surgery, potential improvements through the identification of molecular subtypes of lung cancer and the importance of prevention and early detection.
Impact of Neoadjuvant and Adjuvant Pleural Intensity-Modulated Radiotherapy in Multimodality Treatment for Malignant Pleural Mesothelioma.
Mosleh B, Schwarz S, Cho A, Sinn K, Steindl A, Zöchbauer-Müller S, Köstler WJ, Dieckmann K, Heilmann M, Widder J, Gompelmann D, Aigner C, Klikovits T, Hoda MA.
DOI: 10.1111/1759-7714.70024
To the article
DOI: 10.1111/1759-7714.70024
Prophylactic cranial irradiation for small cell lung cancer in the era of immunotherapy and molecular subtypes.
Pozonec V, Pozonec MD, Aigner C, Widder J, Boettiger K, Megyesfalvi Z, Dome B.
DOI: 10.1097/CCO.0000000000001111
To the article
DOI: 10.1097/CCO.0000000000001111
PD-L1 expression in patients with non-small-cell lung cancer is associated with sex and genetic alterations: A retrospective study within the Caucasian population
Sarova P, Mosleh B, Zehetmayer S, Oberndorfer F, Widder J, Prosch H, Aigner C, Idzko M, Hoda MA, Gompelmann D.
DOI: 10.1111/1759-7714.15336.
To the article
DOI: 10.1111/1759-7714.15336.
High circulating activin A plasma levels are associated with tumour stage and poor survival in treatment-naive lung squamous cell cancer patients.
Sinn K, Elbeialy A, Mosleh B, Aigner C, Schelch K, Laszlo V, Dome B, Hoda MA, Grusch M.
DOI: 10.1016/j.tranon.2024.102153
To the article
DOI: 10.1016/j.tranon.2024.102153
Neoadjuvant nivolumab with or without relatlimab in resectable non-20 small cell lung cancer: a randomized phase 2 trial
Martin Schuler, Kristof Cuppens, Till Plönes, Marcel Wiesweg, Bert Du Pont, Balazs Hegedus, Johannes Köster, Fabian Mairinger, Kaid Darwiche, Annette Paschen, Brigitte Maes, Michel Vanbockrijck, David Lähnemann, Fang Zhao, Hubertus Hautzel, Dirk Theegarten, Koen Hartemink, Henning Reis, Paul Baas, Alexander Schramm, Clemens Aigner.
DOI: 10.1038/s41591-024-02965-0
To the article
DOI: 10.1038/s41591-024-02965-0
Evolutionary trajectories of small cell lung cancer under therapy
George J, Maas L, Abedpour N, Cartolano M, Kaiser L, Fischer RN, Scheel AH, Weber JP, Hellmich M, Bosco G, Volz C, Mueller C, Dahmen I, John F, Alves CP, Werr L, Panse JP, Kirschner M, Engel-Riedel W, Jürgens J, Stoelben E, Brockmann M, Grau S, Sebastian M, Stratmann JA, Kern J, Hummel HD, Hegedüs B, Schuler M, Plönes T, Aigner C, Elter T, Toepelt K, Ko YD, Kurz S, Grohé C, Serke M, Höpker K, Hagmeyer L, Doerr F, Hekmath K, Strapatsas J, Kambartel KO, Chakupurakal G, Busch A, Bauernfeind FG, Griesinger F, Luers A, Dirks W, Wiewrodt R, Luecke A, Rodermann E, Diel A, Hagen V, Severin K, Ullrich RT, Reinhardt HC, Quaas A, Bogus M, Courts C, Nürnberg P, Becker K, Achter V, Büttner R, Wolf J, Peifer M, Thomas RK.
DOI: 10.1038/s41586-024-07177-7
To the article
DOI: 10.1038/s41586-024-07177-7
PD-L1 assessment in lung cancer biopsies-pitfalls and limitations.
Gompelmann D, Sarova P, Mosleh B, Papaporfyriou A, Oberndorfer F, Idzko M, Hoda MA.
DOI: 10.1177/03936155231214273.
To the article
DOI: 10.1177/03936155231214273.